GTX114404
FGD1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX114404
- Zusätzliche Namen:
- FYVE, RhoGEF and PH domain containing 1 , AAS , FGDY , MRXS16 , ZFYVE3
- Anwendung:
- WB
- Konzentration:
- 0.85 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human FGD1. The exact sequence is proprietary.
- Uniprot:
- P98174
- Synonyme:
- AAS;faciogenital dysplasia 1 protein;FGDY;FYVE, RhoGEF and PH domain-containing protein 1;MRXS16;rho/Rac GEF;rho/Rac guanine nucleotide exchange factor FGD1;ZFYVE3;zinc finger FYVE domain-containing protein 3
- Weitere Details:
- FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice