GADD153 antibody [9C8]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX11419
Zusätzliche Namen:: DNA damage inducible transcript 3 , AltDDIT3 , C/EBPzeta , CEBPZ , CHOP , CHOP-10 , CHOP10 , GADD153
Anwendung:: WB, IHC-P, IHC-Fr, IF, ICC, IP
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Mouse
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Mouse, Rabbit, Rat
Buffer:: PBS, 0.1% BSA, 0.05% Sodium azide.
Immunogen:: A bacterially expressed, mouse CHOP fusion protein.
Klon:: 9C8
Uniprot:: P35638
Synonyme:: AltDDIT3;alternative DDIT3 protein;C/EBP zeta;C/EBP-homologous protein;c/EBP-homologous protein 10;C/EBPzeta;CCAAT/enhancer-binding protein homologous protein;CEBPZ;CHOP;CHOP-10;CHOP10;DNA damage-inducible transcript 3 protein;GADD153;growth arrest and DNA damage-inducible protein GADD153
Weitere Details:: This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010]

Versandbedingungen:: Blue Ice