GTX113722
GSTA1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX113722
- Zusätzliche Namen:
- glutathione S-transferase alpha 1 , GST-epsilon , GST2 , GSTA1-1 , GTH1
- Anwendung:
- WB, IHC-P, IF, ICC
- Konzentration:
- 0.86 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human GSTA1. The exact sequence is proprietary.
- Uniprot:
- P08263
- Synonyme:
- 13-hydroperoxyoctadecadienoate peroxidase;androst-5-ene-3,17-dione isomerase;glutathione S-alkyltransferase A1;glutathione S-aryltransferase A1;glutathione S-transferase 2;glutathione S-transferase A1;glutathione S-transferase Ha subunit 1;GST class-alpha member 1;GST HA subunit 1;GST-epsilon;GST2;GSTA1-1;GTH1;S-(hydroxyalkyl)glutathione lyase A1;testicular tissue protein Li 80
- Weitere Details:
- Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice