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  2. Polyclonal

GTX113678

Endothelin 3 antibody [N1C3]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX113678
Zusätzliche Namen:
endothelin 3 , ET-3 , ET3 , HSCR4 , PPET3 , WS4B
Anwendung:
WB
Konzentration:
0.52 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Human
Buffer:
0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human Endothelin 3. The exact sequence is proprietary.
Klon:
N1C3
Uniprot:
P14138
Synonyme:
endothelin-3;ET-3;ET3;HSCR4;PPET3;preproendothelin-3;WS4B
Weitere Details:
The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed. [provided by RefSeq]
Versandbedingungen:
Blue Ice