GTX113555
SSB antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX113555
- Zusätzliche Namen:
- small RNA binding exonuclease protection factor La , LARP3 , La , La/SSB
- Anwendung:
- WB, IHC-P, IF, ICC
- Konzentration:
- 0.48 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human SSB. The exact sequence is proprietary.
- Uniprot:
- P05455
- Synonyme:
- autoantigen La;La;la autoantigen;La ribonucleoprotein;La ribonucleoprotein domain family, member 3;La/SSB;LARP3;lupus La antigen;lupus La protein;sjoegren syndrome type B antigen;Sjogren syndrome antigen B;SS-B;SS-B/La protein
- Weitere Details:
- La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III (see MIM 606007)-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus (SLE; MIM 152700) (Teplova et al., 2006 [PubMed 16387655]).[supplied by OMIM]
- Versandbedingungen:
- Blue Ice