GTX113467
IDH3G antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX113467
- Zusätzliche Namen:
- isocitrate dehydrogenase 3 (NAD(+)) gamma , H-IDHG
- Anwendung:
- IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human IDH3G. The exact sequence is proprietary.
- Uniprot:
- P51553
- Synonyme:
- H-IDHG;IDH-gamma;isocitrate dehydrogenase (NAD(+)) 3 gamma;isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial;isocitrate dehydrogenase 3 (NAD(+)) gamma;isocitrate dehydrogenase 3 (NAD+) gamma;isocitrate dehydrogenase 3 gamma;isocitrate dehydrogenase, NAD(+)-specific, mitochondrial, gamma subunit;isocitric dehydrogenase subunit gamma;NAD (H)-specific isocitrate dehydrogenase gamma subunit;NAD(+)-specific ICDH subunit gamma;NAD+-specific ICDH
- Weitere Details:
- Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice