GTX11343
CASK antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX11343
- Zusätzliche Namen:
- calcium/calmodulin dependent serine protein kinase , CAGH39 , CAMGUK , CMG , FGS4 , LIN2 , MICPCH , MRXSNA , TNRC8 , hCASK
- Anwendung:
- WB, IP
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Canine, Human
- Buffer:
- PBS, 1% BSA, 15mM Sodium azide.
- Immunogen:
- synthetic peptide corresponding to human CASK/LIN-2 sequence, (amino acids 393-409) conjugated to KLH.
- Uniprot:
- O14936
- Synonyme:
- CAGH39;calcium/calmodulin-dependent serin protein kinase;Calcium/calmodulin-dependent serine protein kinase;calcium/calmodulin-dependent serine protein kinase (MAGUK family);calcium/calmodulin-dependent serine protein kinase membrane-associated guanylate kinase;CAMGUK;CMG;FGS4;hCASK;LIN2;MICPCH;MRXSNA;peripheral plasma membrane protein CASK;protein lin-2 homolog;TNRC8;trinucleotide repeat containing 8
- Weitere Details:
- Calmodulin sensitive kinase (CASK/mLIN-2) is a ~112-kDa member of the membrane associated quanylate kinase (MAGUK) protein family with multiple protein binding domains. These include an N-terminal calmodulin kinase (CaMKII) domain and C-terminal PDZ, SH3-, and quanylate kinase domains. CASK possesses both tyrosine kinase and serine/threonine kinase activity. In addition, CASK can form a heterotrimeric complex with Mint (X11or mLIN-10) and Veli (mLIN-7) proteins which is predicted to participate in plasma membrane receptor localization. CASK is localized to neuronal synapses and also interacts with syndecan and neurexin. The guanylate kinase domain of CASK has been shown to interact with the T-box transcription factor, Tbr-1, as a coactivator to induce transcription of genes that contain T-elements.
- Versandbedingungen:
- Blue Ice