NQO1 antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX113336
Zusätzliche Namen:: NAD(P)H quinone dehydrogenase 1 , DHQU , DIA4 , DTD , NMOR1 , NMORI , QR1
Anwendung:: WB, IHC-P
Konzentration:: 0.87 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human NQO1. The exact sequence is proprietary.
Uniprot:: P15559
Synonyme:: azoreductase;DHQU;DIA4;diaphorase (NADH/NADPH) (cytochrome b-5 reductase);diaphorase-4;dioxin-inducible 1;DT-diaphorase;DTD;menadione reductase;NAD(P)H dehydrogenase [quinone] 1;NAD(P)H dehydrogenase, quinone 1;NAD(P)H:menadione oxidoreductase 1;NAD(P)H:Quinone acceptor oxidoreductase type 1;NAD(P)H:quinone oxidoreductase 1;NAD(P)H:quinone oxireductase;NMOR1;NMORI;phylloquinone reductase;QR1;quinone reductase 1
Weitere Details:: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Versandbedingungen:: Blue Ice