GTX113004
RPA32 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX113004
- Zusätzliche Namen:
- replication protein A2 , REPA2 , RP-A p32 , RP-A p34 , RPA32
- Anwendung:
- WB, IHC-P, IF, ICC
- Konzentration:
- 1.64 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human RPA32. The exact sequence is proprietary.
- Uniprot:
- P15927
- Synonyme:
- REPA2;replication factor A protein 2;replication protein A 32 kDa subunit;replication protein A 34 kDa subunit;RF-A protein 2;RP-A p32;RP-A p34;RPA32
- Weitere Details:
- Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
- Versandbedingungen:
- Blue Ice