GTX112673
MUL1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX112673
- Zusätzliche Namen:
- mitochondrial E3 ubiquitin protein ligase 1 , C1orf166 , GIDE , MAPL , MULAN , RNF218
- Anwendung:
- WB, IHC-P, IF, ICC
- Konzentration:
- 0.97 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Insect/Arthropod
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human MUL1. The exact sequence is proprietary.
- Uniprot:
- Q969V5
- Synonyme:
- C1orf166;E3 SUMO-protein ligase MUL1;E3 ubiquitin ligase;E3 ubiquitin-protein ligase MUL1;GIDE;growth inhibition and death E3 ligase;MAPL;mitochondria-anchored protein ligase;mitochondrial E3 ubiquitin ligase 1;mitochondrial ubiquitin ligase activator of NF-kB;mitochondrial ubiquitin ligase activator of NFKB 1;mitochondrial-anchored protein ligase;MULAN;protein Hades;putative NF-kappa-B-activating protein 266;ring finger protein 218;RING-type E3 ubiquitin transferase NFKB 1;RNF218
- Weitere Details:
- E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
- Versandbedingungen:
- Blue Ice