![ABCD2 antibody [N3C2], Internal](https://www.genetex.com/upload/website/prouct_img/normal/GTX112623/GTX112623_40114_20190906_WB_Fraction_competitor_watermark_w_23060500_458.webp)
![ABCD2 antibody [N3C2], Internal](https://www.genetex.com/upload/website/prouct_img/normal/GTX112623/GTX112623_40114_WB_w_23060500_817.webp)
GTX112623
ABCD2 antibody [N3C2], Internal
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX112623
- Zusätzliche Namen:
- ATP binding cassette subfamily D member 2 , ABC39 , ALDL1 , ALDR , ALDRP , hALDR
- Anwendung:
- WB
- Konzentration:
- 0.77 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human ABCD2. The exact sequence is proprietary.
- Klon:
- N3C2
- Uniprot:
- Q9UBJ2
- Synonyme:
- ABC39;adrenoleukodystrophy-like 1;adrenoleukodystrophy-related protein;ALDL1;ALDR;ALDRP;ATP-binding cassette sub-family D member 2;ATP-binding cassette, sub-family D (ALD), member 2;hALDR
- Weitere Details:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice