GTX112397
AOC2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX112397
- Zusätzliche Namen:
- amine oxidase copper containing 2 , DAO2 , RAO , SSAO
- Anwendung:
- IF, ICC
- Konzentration:
- 0.94 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human AOC2. The exact sequence is proprietary.
- Uniprot:
- O75106
- Synonyme:
- Amine oxidase [copper-containing];amine oxidase, copper containing 2 (retina-specific);DAO2;RAO;retina-specific copper amine oxidase;semicarbazide-sensitive amine oxidase;SSAO
- Weitere Details:
- Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice