Dbs antibody [N1N2], N-term

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX112306
Zusätzliche Namen:: MCF.2 cell line derived transforming sequence like , ARHGEF14 , DBS , OST
Anwendung:: WB
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the N-terminus region of human Dbs. The exact sequence is proprietary.
Klon:: N1N2
Uniprot:: O15068
Synonyme:: ARHGEF14;DBL's big sister;DBS;guanine nucleotide exchange factor DBS;MCF2 transforming sequence-like protein;MCF2-transforming sequence-like protein;OST
Weitere Details:: Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42.