RENT1 antibody [C1C2], Internal

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX112241
Zusätzliche Namen:: UPF1 RNA helicase and ATPase , HUPF1 , NORF1 , RENT1 , pNORF1 , smg-2
Anwendung:: WB
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human RENT1. The exact sequence is proprietary.
Klon:: C1C2
Uniprot:: Q92900
Synonyme:: ATP-dependent helicase RENT1;delta helicase;HUPF1;nonsense mRNA reducing factor 1;NORF1;pNORF1;regulator of nonsense transcripts 1;RENT1;smg-2;smg-2 homolog, nonsense mediated mRNA decay factor;up-frameshift mutation 1 homolog;up-frameshift suppressor 1 homolog;UPF1 regulator of nonsense transcripts homolog;UTF;yeast Upf1p homolog
Weitere Details:: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq]

Versandbedingungen:: Blue Ice