GTX111946
M-CSF Receptor antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX111946
- Zusätzliche Namen:
- colony stimulating factor 1 receptor , C-FMS , CD115 , CSF-1R , CSFR , FIM2 , FMS , HDLS , M-CSF-R
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human, Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Mouse
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the Intracellular domain of human CSF1R. The exact sequence is proprietary.
- Uniprot:
- P07333
- Synonyme:
- BANDDOS;C-FMS;CD115;CD115 antigen;CSF-1 receptor;CSF-1R;CSFR;FIM2;FMS;FMS proto-oncogene;HDLS;M-CSF-R;macrophage colony stimulating factor I receptor;macrophage colony-stimulating factor 1 receptor;McDonough feline sarcoma viral (v-fms) oncogene homolog;proto-oncogene c-Fms
- Weitere Details:
- The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice