Cyclin T2 antibody [C2C3], C-term

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX111944
Zusätzliche Namen:: cyclin T2 , CYCT2
Anwendung:: WB, IHC-P, IF, ICC
Konzentration:: 0.51 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the C-terminus region of human cyclin T2. The exact sequence is proprietary.
Klon:: C2C3
Uniprot:: O60583
Synonyme:: cyclin T2a;cyclin T2b;cyclin-T2;CYCT2;SDS-stable vimentin-bound DNA fragment HEF42VIM22;subunit of positive elongation transcription factor b
Weitere Details:: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. Two alternatively spliced transcript variants, which encode distinct isoforms, have been described. [provided by RefSeq]

Versandbedingungen:: Blue Ice