BCL2L10 antibody [N2C2], Internal

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX111872
Zusätzliche Namen:: BCL2 like 10 , BCL-B , Boo , Diva , bcl2-L-10
Anwendung:: WB, IHC-P, IF, ICC
Konzentration:: 1.32 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 20% Glycerol, 0.025% ProClin 300.
Immunogen:: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human BCL2L10. The exact sequence is proprietary.
Klon:: N2C2
Uniprot:: Q9HD36
Synonyme:: anti-apoptotic protein NrH;apoptosis regulator Bcl-B;bcl-2-like protein 10;BCL-B;bcl2-L-10;BCL2-like 10 (apoptosis facilitator);Boo;death inducer binding to vBcl-2 and Apaf-1;Diva
Weitere Details:: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq]

Versandbedingungen:: Blue Ice