Mre11 antibody [C1C3-2]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX111814
Zusätzliche Namen:: MRE11 homolog, double strand break repair nuclease , ATLD , HNGS1 , MRE11A , MRE11B
Anwendung:: WB, IF, ICC, IP
Konzentration:: 0.57 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the C-terminus region of human Mre11. The exact sequence is proprietary.
Klon:: C1C3-2
Uniprot:: P49959
Synonyme:: AT-like disease;ATLD;DNA recombination and repair protein;double-strand break repair protein MRE11;double-strand break repair protein MRE11A;endo/exonuclease Mre11;HNGS1;meiotic recombination 11 homolog 1;meiotic recombination 11 homolog A;MRE11 double strand break repair nuclease A;MRE11 homolog 1;MRE11 homolog A, double strand break repair nuclease;MRE11 homolog, double strand break repair nuclease A;MRE11 meiotic recombination 11 homolog A;MRE11 meiotic recombination 11-like protein A;MRE11A;MRE11B
Weitere Details:: This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq]

Versandbedingungen:: Blue Ice