NDUFA5 antibody [N1C3]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX111016
Zusätzliche Namen:: NADH:ubiquinone oxidoreductase subunit A5 , B13 , CI-13KD-B , CI-13kB , NUFM , UQOR13
Anwendung:: WB, IHC-P
Konzentration:: 1.47 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: PBS, 20% Glycerol, 0.025% ProClin 300.
Immunogen:: Full length human NDUFA5 Recombinant protein.
Klon:: N1C3
Uniprot:: Q16718
Synonyme:: B13;CI-13kB;CI-13KD-B;complex I 13kDa subunit B;complex I subunit B13;Complex I-13kD-B;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5;NADH-ubiquinone oxidoreductase 13 kDa-B subunit;NUFM;type I dehydrogenase;ubiquinone reductase;UQOR13
Weitere Details:: The human NDUFA5 gene codes for the B13 subunit of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. The high degree of conservation of NDUFA5 extending to plants and fungi indicates its functional significance in the enzyme complex. The protein localizes to the inner mitochondrial membrane as part of the 7 component-containing, water soluble "iron-sulfur protein" (IP) fraction of complex I, although its specific role is unknown. It is assumed to undergo post-translational removal of the initiator methionine and N-acetylation of the next amino acid. The predicted secondary structure is primarily alpha helix, but the carboxy-terminal half of the protein has high potential to adopt a coiled-coil form. The amino-terminal part contains a putative beta sheet rich in hydrophobic amino acids that may serve as mitochondrial import signal. Related pseudogenes have also been identified on four other chromosomes. [provided by RefSeq]

Versandbedingungen:: Blue Ice