MYO6 antibody [MUD-19]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX11095
Zusätzliche Namen:: myosin VI , DFNA22 , DFNB37 , Myo6-007 , Myo6-008
Anwendung:: ELISA, IHC, WB, IP
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Mouse, Rat
Buffer:: PBS, 1% BSA, 15mM Sodium azide.
Immunogen:: synthetic peptide corresponding to amino acids 291-302 of human myosin VI.
Klon:: MUD-19
Uniprot:: Q9UM54
Synonyme:: DFNA22;DFNB37;unconventional myosin-6;unconventional myosin-VI
Weitere Details:: Myosins belong to a superfamily of actin based motor proteins comprising at least 15 or more classes. There are two main groups of myosins: the conventional (class II) and the unconventional myosins. Myosin VI is a relatively abundant widespread unconventional myosin composed of an N-terminal motor domain, a light chain binding neck region, a coil-coiled region, and a highly conserved C-terminal domain. At the converter region between the catalytic head and the neck region of myosin VI, there is a characteristic linker of approximately 50 amino acids. Native myosin VI is apparently a two-headed dimer of the heavy chains with each heavy chain bound to calmodulin light chain. Myosin VI is a unique reverse actin motor in vitro i.e. to display motility towards the pointed (minus) ends of actin filaments, a direction opposite to all other currently known myosins.

Versandbedingungen:: Blue Ice