GTX110514
TIGAR antibody [C2C3], C-term

Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX110514
- Zusätzliche Namen:
- TP53 induced glycolysis regulatory phosphatase , C12orf5 , FR2BP
- Anwendung:
- WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TIGAR. The exact sequence is proprietary.
- Klon:
- C2C3
- Uniprot:
- Q9NQ88
- Synonyme:
- C12orf5;FR2BP;fructose-2,6-bisphosphatase TIGAR;fructose-2,6-bisphosphate 2-phosphatase;probable fructose-2,6-bisphosphatase TIGAR;TP53-induced glycolysis and apoptosis regulator;TP53-induced glycolysis regulatory phosphatase;transactivated by NS3TP2 protein
- Weitere Details:
- This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice
![TIGAR antibody [C2C3], C-term](https://www.genetex.com/upload/website/prouct_img/normal/GTX110514/GTX110514_40002_IHC_w_23060500_341.webp)
![TIGAR antibody [C2C3], C-term](https://www.genetex.com/upload/website/prouct_img/normal/GTX110514/GTX110514_WB_w_23060500_835.webp)