TLE1 antibody [N2C1], Internal

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX110092
Zusätzliche Namen:: TLE family member 1, transcriptional corepressor , ESG , ESG1 , GRG1
Anwendung:: WB, IF, ICC
Konzentration:: 0.92 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Rat
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human TLE1. The exact sequence is proprietary.
Klon:: N2C1
Uniprot:: Q04724
Synonyme:: E(Sp1) homolog;enhancer of split groucho-like protein 1;ESG;ESG1;GRG1;transducin like enhancer of split 1;transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila);transducin-like enhancer protein 1
Weitere Details:: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.