PAK3 antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX109991
Zusätzliche Namen:: p21 (RAC1) activated kinase 3 , ARA , MRX30 , MRX47 , OPHN3 , PAK-3 , PAK3beta , bPAK , beta-PAK
Anwendung:: WB
Konzentration:: 0.74 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human PAK3. The exact sequence is proprietary.
Uniprot:: O75914
Synonyme:: adriamycin resistance-associated;ARA;beta-PAK;bPAK;MRX30;MRX47;oligophrenin-3;OPHN3;p21 (CDKN1A)-activated kinase 3;p21 protein (Cdc42/Rac)-activated kinase 3;p21-activated kinase 3;PAK-3;PAK3beta;serine/threonine-protein kinase PAK 3;XLID30
Weitere Details:: PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Versandbedingungen:: Blue Ice