DUSP26 antibody [N1C1]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX109283
Zusätzliche Namen:: dual specificity phosphatase 26 , DSP-4 , DUSP24 , LDP-4 , MKP-8 , MKP8 , NATA1 , NEAP , SKRP3
Anwendung:: WB, IF, ICC, IP
Konzentration:: 1.52 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: PBS, 20% Glycerol, 0.025% ProClin 300.
Immunogen:: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human DUSP26. The exact sequence is proprietary.
Klon:: N1C1
Uniprot:: Q9BV47
Synonyme:: DSP-4;dual specificity phosphatase 26 (putative);dual specificity phosphatase SKRP3;dual specificity protein phosphatase 26;DUSP24;LDP-4;LDP4;low-molecular-mass dual-specificity phosphatase 4;MAP kinase phosphatase 8;mitogen-activated protein kinase phosphatase 8;MKP-8;MKP8;NATA1;NEAP;neuroendocrine-associated phosphatase;Novel amplified gene in thyroid anaplastic cancer;SKRP3
Weitere Details:: Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).

Versandbedingungen:: Blue Ice