UBE2D1 antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX109257
Zusätzliche Namen:: ubiquitin conjugating enzyme E2 D1 , E2(17)KB1 , SFT , UBC4/5 , UBCH5 , UBCH5A
Anwendung:: WB, IHC-P, IF, ICC
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Full length human UBE2D1 Recombinant protein.
Uniprot:: P51668
Synonyme:: (E3-independent) E2 ubiquitin-conjugating enzyme D1;E2 ubiquitin-conjugating enzyme D1;E2(17)KB1;SFT;stimulator of Fe transport;UBC4/5;UBC4/5 homolog;UBCH5;UBCH5A;ubiquitin carrier protein D1;ubiquitin conjugating enzyme E2D 1;ubiquitin-conjugating enzyme E2 D1;ubiquitin-conjugating enzyme E2-17 kDa 1;ubiquitin-conjugating enzyme E2(17)KB 1;ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast);ubiquitin-protein ligase D1
Weitere Details:: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. [provided by RefSeq]

Versandbedingungen:: Blue Ice