GTX10905
XPA antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX10905
- Zusätzliche Namen:
- XPA, DNA damage recognition and repair factor , XP1 , XPAC
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Crude Serum
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Serum, 0.09% Sodium azide.
- Immunogen:
- Recombinant human XPA
- Uniprot:
- P23025
- Synonyme:
- DNA repair protein complementing XP-A cells;xeroderma pigmentosum group A-complementing protein;xeroderma pigmentosum, complementation group A;XP1;XPAC
- Weitere Details:
- This gene encodes a zinc finger protein plays a central role in nucleotide excision repair (NER), a specialized type of DNA repair. NER is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens and chemotherapeutic drugs. The encoded protein interacts with DNA and several NER proteins, acting as a scaffold to assemble the NER incision complex at sites of DNA damage. Mutations in this gene cause Xeroderma pigmentosum complementation group A (XP-A), an autosomal recessive skin disorder featuring hypersensitivity to sunlight and increased risk for skin cancer. [provided by RefSeq, Aug 2017]
- Versandbedingungen:
- Blue Ice