RPA70 antibody [C1C3]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX108749
Zusätzliche Namen:: replication protein A1 , HSSB , MST075 , REPA1 , RF-A , RP-A , RPA70
Anwendung:: WB, IHC-P, IF, ICC, IP
Konzentration:: 0.4 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
Immunogen:: Recombinant protein encompassing a sequence within the C-terminus region of human RPA70. The exact sequence is proprietary.
Klon:: C1C3
Uniprot:: P27694
Synonyme:: HSSB;MST075;MSTP075;REPA1;replication factor A protein 1;replication protein A 70 kDa DNA-binding subunit;replication protein A1, 70kDa;RF-A;RF-A protein 1;RP-A;RP-A p70;RPA70;single-stranded DNA-binding protein
Weitere Details:: Plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing. Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.

Versandbedingungen:: Blue Ice