Fibulin 5 antibody [C3], C-term

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX108531
Zusätzliche Namen:: fibulin 5 , ADCL2 , ARCL1A , ARMD3 , DANCE , EVEC , FIBL-5 , HNARMD , UP50
Anwendung:: WB
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Fibulin 5. The exact sequence is proprietary.
Klon:: C3
Uniprot:: Q9UBX5
Synonyme:: ADCL2;ARCL1A;ARMD3;DANCE;developmental arteries and neural crest EGF-like protein;embryonic vascular EGF-like repeat-containing protein;EVEC;FIBL-5;fibulin-5;HNARMD;testis tissue sperm-binding protein Li 75n;UP50;urine p50 protein
Weitere Details:: The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq]

Versandbedingungen:: Blue Ice