TL1A antibody [C2C3], C-term

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX108463
Zusätzliche Namen:: TNF superfamily member 15 , TL1 , TL1A , TNLG1B , VEGI , VEGI192A
Anwendung:: WB
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Synthetic peptide encompassing a sequence within the Extracellular domain of human TL1A. The exact sequence is proprietary.
Klon:: C2C3
Uniprot:: O95150
Synonyme:: TL1;TL1A;TNF ligand-related molecule 1;TNF superfamily ligand TL1A;TNLG1B;tumor necrosis factor (ligand) superfamily, member 15;tumor necrosis factor ligand 1B;tumor necrosis factor ligand superfamily member 15;tumor necrosis factor superfamily member 15;vascular endothelial cell growth inhibitor;vascular endothelial growth inhibitor-192A;VEGI;VEGI192A
Weitere Details:: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. An additional isoform encoded by an alternatively spliced transcript variant has been reported but the sequence of this transcript has not been determined. [provided by RefSeq]

Versandbedingungen:: Blue Ice