GTX108405
Inhibin beta A antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX108405
- Zusätzliche Namen:
- inhibin subunit beta A , EDF , FRP
- Anwendung:
- WB, IHC-P, IF, ICC
- Konzentration:
- 1.59 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Inhibin beta A. The exact sequence is proprietary.
- Uniprot:
- P08476
- Synonyme:
- activin beta-A chain;EDF;erythroid differentiation factor;erythroid differentiation protein;follicle-stimulating hormone-releasing protein;FRP;FSH-releasing protein;inhibin beta A chain;inhibin beta A subunit;inhibin, beta A (activin A, activin AB alpha polypeptide);Inhibin, beta-1
- Weitere Details:
- The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice