GTX108015
PTCH1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX108015
- Zusätzliche Namen:
- patched 1 , BCNS , NBCCS , PTC , PTC1 , PTCH
- Anwendung:
- WB
- Konzentration:
- 0.85 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Synthetic peptide encompassing a sequence within the Intracellular domain of human Patched 1. The exact sequence is proprietary.
- Uniprot:
- Q13635
- Synonyme:
- BCNS;NBCCS;protein patched homolog 1;PTC;PTC1;PTCH
- Weitere Details:
- This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice