TFB2M antibody [C3], C-term

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX107714
Zusätzliche Namen:: transcription factor B2, mitochondrial , Hkp1 , mtTFB2
Anwendung:: WB
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TFB2M. The exact sequence is proprietary.
Klon:: C3
Uniprot:: Q9H5Q4
Synonyme:: dimethyladenosine transferase 2, mitochondrial;h-mtTFB;h-mtTFB2;HCV NS5A-transactivated protein 5;hepatitis C virus NS5A-transactivated protein 5;Hkp1;hTFB2M;mitochondrial 12S rRNA dimethylase 2;mitochondrial transcription factor B2;mtTFB2;S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2
Weitere Details:: S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.

Versandbedingungen:: Blue Ice