![RGS14 antibody [C3], C-term](https://www.genetex.com/upload/website/prouct_img/normal/GTX106412/GTX106412_39890_IHC_w_23060120_940.webp)
![RGS14 antibody [C3], C-term](https://www.genetex.com/upload/website/prouct_img/normal/GTX106412/GTX106412_39890_WB_w_23060120_225.webp)
GTX106412
RGS14 antibody [C3], C-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX106412
- Zusätzliche Namen:
- regulator of G protein signaling 14
- Anwendung:
- WB, IHC-P
- Konzentration:
- 0.93 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RGS14. The exact sequence is proprietary.
- Klon:
- C3
- Uniprot:
- O43566
- Synonyme:
- regulator of G-protein signaling 14
- Weitere Details:
- This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice