![LXR alpha antibody [C3], C-term](https://www.genetex.com/upload/website/prouct_img/normal/GTX106380/GTX106380_WB_w_23060120_893.webp)
GTX106380
LXR alpha antibody [C3], C-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX106380
- Zusätzliche Namen:
- nuclear receptor subfamily 1 group H member 3 , LXR-a , LXRA , RLD-1
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 10% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human LXR alpha. The exact sequence is proprietary.
- Klon:
- C3
- Uniprot:
- Q13133
- Synonyme:
- liver X nuclear receptor alpha variant 1;Liver X receptor alpha;LXR-a;LXRA;Nuclear receptor subfamily 1 group H member 3;oxysterols receptor LXR-alpha;RLD-1
- Weitere Details:
- The liver X receptors, LXRA and LXRB (NR1H2; MIM 600380), form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM]
- Versandbedingungen:
- Blue Ice