![MTA2 antibody [C3], C-term](https://www.genetex.com/upload/website/prouct_img/normal/GTX106367/GTX106367_39694_IFA_w_23060120_220.webp)
![MTA2 antibody [C3], C-term](https://www.genetex.com/upload/website/prouct_img/normal/GTX106367/GTX106367_WB_w_23060120_421.webp)
GTX106367
MTA2 antibody [C3], C-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX106367
- Zusätzliche Namen:
- metastasis associated 1 family member 2 , MTA1L1 , PID
- Anwendung:
- WB, IF, ICC
- Konzentration:
- 0.67 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 10% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human MTA2. The exact sequence is proprietary.
- Klon:
- C3
- Uniprot:
- O94776
- Synonyme:
- metastasis -associated gene 1-like 1;metastasis associated gene family, member 2;metastasis-associated 1-like 1;metastasis-associated protein 2;metastasis-associated protein MTA2;MTA1-L1 protein;MTA1L1;p53 target protein in deacetylase complex;PID
- Weitere Details:
- This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacteylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice