GTX106348
SorLA antibody [C3], C-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX106348
- Zusätzliche Namen:
- sortilin related receptor 1 , C11orf32 , LR11 , LRP9 , SORLA , SorLA-1 , gp250
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Buffer:
- PBS, 10% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SorLA. The exact sequence is proprietary.
- Klon:
- C3
- Uniprot:
- Q92673
- Synonyme:
- C11orf32;gp250;LDLR relative with 11 ligand-binding repeats;low-density lipoprotein receptor relative with 11 ligand-binding repeats;LR11;LRP9;mosaic protein LR11;SORLA;SorLA-1;sortilin-related receptor;sortilin-related receptor, L(DLR class) A repeats containing;sorting protein-related receptor containing LDLR class A repeats
- Weitere Details:
- This gene encodes a protein that belongs to the families of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins, of low density lipoprotein receptor (LDLR) proteins, and of fibronectin type III repeats proteins. In addition to VPS10, LDLR and fibronectin type 3 domains, this protein also includes an epidermal growth factor precursor-like module, a single transmembrane segment and a cytoplasmic tail with features similar to endocytosis- and sorting-competent receptors. Members of the VPS10 domain-containing receptor family are large with many exons but the CDS lengths are usually less than 3700 nt; this gene is an exception to the pattern with a CDS length greater than 6600 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. The encoded protein is mainly intracellular and localizes in the paranuclear compartment. It is synthesized as a preproprotein, and when the propeptide is still attached, no binding occurs to the VPS10 domain. This gene is strongly expressed in the central nervous system. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice