GTX106235
CD2AP antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX106235
- Zusätzliche Namen:
- CD2 associated protein , CMS
- Anwendung:
- WB, IHC-P, IF, ICC
- Konzentration:
- 0.17 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human CD2AP. The exact sequence is proprietary.
- Uniprot:
- Q9Y5K6
- Synonyme:
- adapter protein CMS;cas ligand with multiple SH3 domains;Cas ligand with multiple Src homology 3 (SH3) domains;CD2-associated protein;CMS
- Weitere Details:
- This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice