GTX105331
COPG antibody [N3C2], Internal
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX105331
- Zusätzliche Namen:
- coatomer protein complex subunit gamma 1 , COPG
- Anwendung:
- WB
- Konzentration:
- 0.42 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human COPG. The exact sequence is proprietary.
- Klon:
- N3C2
- Uniprot:
- Q9Y678
- Synonyme:
- coat protein gamma-cop;coatomer protein complex subunit gamma 1;coatomer protein complex, subunit gamma;coatomer subunit gamma;coatomer subunit gamma-1;COPG;gamma-1-coat protein;gamma-1-COP;gamma-coat protein;gamma-COP
- Weitere Details:
- The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
- Versandbedingungen:
- Blue Ice