GTX10519
FADD antibody [FD19]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX10519
- Zusätzliche Namen:
- Fas associated via death domain , GIG3 , MORT1
- Anwendung:
- ELISA, WB, IP
- Konzentration:
- 2 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS, 15mM Sodium azide.
- Immunogen:
- purified recombinant human FADD.
- Klon:
- FD19
- Uniprot:
- Q13158
- Synonyme:
- Fas (TNFRSF6)-associated via death domain;FAS-associated death domain protein;Fas-associating death domain-containing protein;Fas-associating protein with death domain;GIG3;growth-inhibiting gene 3 protein;Mediator of receptor induced toxicity;mediator of receptor-induced toxicity;MORT1;Protein FADD
- Weitere Details:
- FADD (Fas Associated Death Domain) is an apoptosis adapter molecule enabling transduction of the apoptosis signal initiated via the FasL/Fas receptor interaction. The protein contains a C-terminal death domain that interacts with the Fas receptor death domain. The N-terminus contains a death effectors domain (DED, which recruits caspase to the death inducing signaling complex (DISC) and initiates the apoptotic caspase cascade. FADD is implicated in non-apoptotic cellular pathways such as the regulation of cell cycle machinery in T lymphocytes. This is connected to the phosphorylation state of FADD and to the FasL/TRAIL-induced transcriptional activation of c-fos protooncogene. FADD also interacts with the hepatitis C virus core protein in the HEK-293 cell line.
- Versandbedingungen:
- Blue Ice