MAPKAP Kinase 3 antibody [N2C3]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX105147
Zusätzliche Namen:: mitogen-activated protein kinase-activated protein kinase 3 , 3PK , MAPKAP-K3 , MAPKAP3 , MAPKAPK-3 , MDPT3 , MK-3
Anwendung:: WB, IF, ICC
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human MAPKAP Kinase 3. The exact sequence is proprietary.
Klon:: N2C3
Uniprot:: Q16644
Synonyme:: 3PK;chromosome 3p kinase;MAP kinase-activated protein kinase 3;MAPKAP kinase 3;MAPKAP-K3;MAPKAP3;MAPKAPK-3;MDPT3;mitogen-activated protein kinase-activated protein kinase 3;MK-3;MK3
Weitere Details:: This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. [provided by RefSeq]

Versandbedingungen:: Blue Ice