![PSMF1 antibody [C2C3], C-term](https://www.genetex.com/upload/website/prouct_img/normal/GTX104760/GTX104760_39666_20200821_WB_TPM_watermark_w_23060120_941.webp)
![PSMF1 antibody [C2C3], C-term](https://www.genetex.com/upload/website/prouct_img/normal/GTX104760/GTX104760_40205_20200821_WB_TPM_watermark_w_23060120_616.webp)
GTX104760
PSMF1 antibody [C2C3], C-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX104760
- Zusätzliche Namen:
- proteasome inhibitor subunit 1 , PI31
- Anwendung:
- WB
- Konzentration:
- 1.02 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PSMF1. The exact sequence is proprietary.
- Klon:
- C2C3
- Uniprot:
- Q92530
- Synonyme:
- PI31;proteasome (prosome, macropain) inhibitor subunit 1 (PI31);proteasome inhibitor PI31 subunit
- Weitere Details:
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice