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  2. Polyclonal

GTX104681

NOTCH3 antibody [C3], C-term

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX104681
Zusätzliche Namen:
notch receptor 3 , CADASIL , CADASIL1 , CASIL , IMF2 , LMNS
Anwendung:
WB
Konzentration:
5.26 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Protein A Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Human
Buffer:
0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:
Synthetic peptide encompassing a sequence within the Intracellular domain of human Notch3. The exact sequence is proprietary.
Klon:
C3
Uniprot:
Q9UM47
Synonyme:
CADASIL;CADASIL1;CASIL;IMF2;LMNS;neurogenic locus notch homolog protein 3;notch 3;Notch homolog 3
Weitere Details:
This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq]
Versandbedingungen:
Blue Ice