GTX10441
ARTS antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX10441
- Zusätzliche Namen:
- septin 4 , ARTS , BRADEION , C17orf47 , CE5B3 , H5 , MART , PNUTL2 , SEP4 , hCDCREL-2 , hucep-7
- Anwendung:
- WB, IP
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 15mM Sodium azide.
- Immunogen:
- synthetic peptide corresponding to the C-terminal region of human ARTS (amino acids 247-266 with N-terminal added lysine) conjugated to KLH.
- Uniprot:
- O43236
- Synonyme:
- apoptosis-related protein in the TGF-beta signaling pathway;ARTS;BRADEION;bradeion beta;brain protein H5;C17orf47;CE5B3;CE5B3 beta;cell division control-related protein 2;cerebral protein 7;H5;hCDCREL-2;hucep-7;MART;peanut-like protein 2;PNUTL2;SEP4;SEPT4;septin-4;septin-M;uncharacterized protein C17orf47
- Weitere Details:
- Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF beta signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF beta and, to a lesser extent, by other apoptotic agents, such as TNF alpha and Fas ligand.
- Versandbedingungen:
- Blue Ice