GTX103453
tPA antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX103453
- Zusätzliche Namen:
- plasminogen activator, tissue type , T-PA , TPA
- Anwendung:
- WB, IHC-P
- Konzentration:
- 0.15 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human tPA. The exact sequence is proprietary.
- Uniprot:
- P00750
- Synonyme:
- alteplase;plasminogen/activator kringle;reteplase;T-PA;t-plasminogen activator;tissue-type plasminogen activator;TPA
- Weitere Details:
- This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice