GTX103229
NBS1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX103229
- Zusätzliche Namen:
- nibrin , AT-V1 , AT-V2 , ATV , NBS , NBS1 , P95
- Anwendung:
- WB, IF, ICC, IP
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human NBS1. The exact sequence is proprietary.
- Uniprot:
- O60934
- Synonyme:
- AT-V1;AT-V2;ATV;cell cycle regulatory protein p95;NBS;NBS1;nibrin;Nijmegen breakage syndrome 1 (nibrin);Nijmegen breakage syndrome protein 1;P95;p95 protein of the MRE11/RAD50 complex
- Weitere Details:
- Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice