MUTYH antibody [N3C3]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX103185
Zusätzliche Namen:: mutY DNA glycosylase , MYH
Anwendung:: WB, IF, ICC
Konzentration:: 0.16 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human MUTYH. The exact sequence is proprietary.
Klon:: N3C3
Uniprot:: Q9UIF7
Synonyme:: A/G-specific adenine DNA glycosylase;adenine DNA glycosylase;mutY homolog;mutY-like protein;MYH
Weitere Details:: This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]