Skip to content

Datenblatt ansehen

open_in_new
  1. Alles ansehen
  2. Polyclonal

GTX103166

IL12 Receptor beta2 antibody [N3C2], Internal

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX103166
Zusätzliche Namen:
interleukin 12 receptor subunit beta 2
Anwendung:
WB
Konzentration:
1 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Human
Buffer:
0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human IL12 Receptor beta2. The exact sequence is proprietary.
Klon:
N3C2
Uniprot:
Q99665
Synonyme:
IL-12 receptor subunit beta-2;IL-12R subunit beta-2;interleukin 12 receptor, beta 2;interleukin-12 receptor beta-2 chain;interleukin-12 receptor subunit beta-2
Weitere Details:
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. [provided by RefSeq]
Versandbedingungen:
Blue Ice