GTX103166
IL12 Receptor beta2 antibody [N3C2], Internal

Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX103166
- Zusätzliche Namen:
- interleukin 12 receptor subunit beta 2
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human IL12 Receptor beta2. The exact sequence is proprietary.
- Klon:
- N3C2
- Uniprot:
- Q99665
- Synonyme:
- IL-12 receptor subunit beta-2;IL-12R subunit beta-2;interleukin 12 receptor, beta 2;interleukin-12 receptor beta-2 chain;interleukin-12 receptor subunit beta-2
- Weitere Details:
- The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice
![IL12 Receptor beta2 antibody [N3C2], Internal](https://www.genetex.com/upload/website/prouct_img/normal/GTX103166/GTX103166_WB_w_23060119_282.webp)