GTX10312
ATR antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX10312
- Zusätzliche Namen:
- ATR , ATR serine/threonine kinase , FCTCS , FRP1 , MEC1 , SCKL , SCKL1
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Tris-Citrate/Phosphate, 0.1% Sodium azide.
- Immunogen:
- Synthetic peptide representing a portion of the protein encoded within exon 5 (LocusLink ID 545).
- Uniprot:
- Q13535
- Synonyme:
- ataxia telangiectasia and Rad3-related protein;FCTCS;FRAP-related protein 1;FRAP-related protein-1;FRP1;MEC1;MEC1, mitosis entry checkpoint 1, homolog;SCKL;SCKL1;serine/threonine-protein kinase ATR
- Weitere Details:
- The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]
- Versandbedingungen:
- Blue Ice