GTX103005
CSE1L antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX103005
- Zusätzliche Namen:
- chromosome segregation 1 like , CAS , CSE1 , XPO2
- Anwendung:
- WB, IHC-P, IF, ICC, IP
- Konzentration:
- 0.4 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human CSE1L. The exact sequence is proprietary.
- Uniprot:
- P55060
- Synonyme:
- CAS;cellular apoptosis susceptibility protein;chromosome segregation 1-like protein;CSE1;CSE1 chromosome segregation 1-like;epididymis secretory sperm binding protein;exp2;exportin-2;importin-alpha re-exporter;XPO2
- Weitere Details:
- Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice