COL1A2 antibody [C2C3], C-term

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX102996
Zusätzliche Namen:: collagen type I alpha 2 chain , EDSARTH2 , EDSCV , OI4
Anwendung:: WB, IF, ICC
Konzentration:: 0.43 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Fish, Human, Mouse
Buffer:: PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
Immunogen:: Recombinant protein encompassing a sequence within the C-terminus region of human COL1A2. The exact sequence is proprietary.
Klon:: C2C3
Uniprot:: P08123
Synonyme:: alpha 2 type I procollagen;alpha 2(I) procollagen;alpha 2(I)-collagen;alpha-2 type I collagen;collagen alpha-2(I) chain;collagen I, alpha-2 polypeptide;collagen of skin, tendon and bone, alpha-2 chain;collagen, type I, alpha 2;EDSARTH2;EDSCV;epididymis secretory sperm binding protein;OI4;type I procollagen
Weitere Details:: This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish]

Versandbedingungen:: Blue Ice